The entries of “Technologies made in Vienna” are displayed in the project language.
Technologies from Vienna
enGenes Biotech GmbH
enGenes Biotech – delivering cost-effective recombinant protein productionenGenes develops customized solutions for the cost-effective production of recombinant proteins in microbial expression systems. We combine a vast experience in cutting-edge genetic engineering with a broad expertise in bioprocess engineering to deliver best-in-class protein expression systems. Based on a strong understanding for the requirements of the biotech industry and extensive knowledge and method portfolio, enGenes delivers improved host cell lines, plasmid expression vectors and optimized production processes to maximize bio-process efficacy.
Integrative bioprocess development for biosimilar productionThe Austrian biotech company enGenes Biotech GmbH has developed a novel, proprietary enGenes-X-press technology, which describes a non-growth associated E. coli-based protein production system that enables manufacturing of recombinant proteins with increased specific and consequently high volumetric yields. enGenes Biotech has developed a technology where the recombinant E. coli cells are forced into a “resting state” (cells do not grow and divide any more), which is why the whole energy is channeled from growth to recombinant protein production leading to higher product yields (see Figure 1 in the attachment). Thus, the first key issue to make the recombinant production of Fabs in the periplasm of E. coli an easier task seems to be solved. The remaining challenge is to understand the effects of process parameters on this unique microbial protein production system.
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